Our Capabilities

17 September 2024
CHAPTER 4 . OUR SMOKELESS SCIENCE

Our Capabilities

Our transformation is underpinned by our purpose of reducing the health impact of our business. 


To enable our transformation, we strive to encourage adult smokers, who would otherwise continue to smoke, to switch to reduced-risk*† Smokeless Products. Our focus continues to be on finding and developing new innovations and products and establishing databased insights that evolve our innovation strategy to create products that could reduce the burden on global public health.

We are dedicated to innovation through every thread of the company, and we believe that success and longevity will be achieved through a science-based transformation.

Over the last decade, we have embedded the innovation of Smokeless Products into our organisation. This ensures the correct behaviours, structures and practices are in place to enable innovation to thrive. Added to that has been the evolution of our technical capabilities to enable the development of consumer loved products and the increased capabilities to scientifically assess their impact on public health.

We are in our eighth decade of research and development having established R&D sites in the U.S. and UK in the 1950s. Back then, when BAT principally sold cigarettes, the focus was predominantly on the chemical and toxicological evaluation of cigarette smoke. With the advent of improved analytical techniques, novel spectroscopic methods enabled the accurate identification of individual compounds in cigarette smoke, even those present at very low (micro- or nanogram) levels.

Biology advanced with the creation of novel laboratory methodologies that could assess the toxicological impact of cigarette smoke while in parallel, biotechnology and specifically molecular biology techniques were applied to mapping the tobacco genome. The first clinical studies were conducted in the 1980s and 1990s to assess the pharmacokinetics and pharmacodynamics of novel tobacco products and with the advent of novel Heated Products, more sophisticated clinical studies were conducted to enable the measurement of Biomarkers of Exposure.

A glimpse of our science through time:

American flag waving on beach

1953

Reynolds R&D established

British flag waving in breeze

1956

Southampton R&D established

Scientists working in laboratory

1960s

Chemistry dominates

Scientist examining sample in lab

1970s

Greater focus on smoking behaviour and biology

Testing equipment

1980s

Biotechnology embraced

Researchers analyzing data in lab

1990s

Increasingly sophisticated analytical techniques to measure smoke constituents

Scientist using breathing apparatus

2000s

Advances in biology: biomarkers, diverse cell and tissue systems 

Electronic cigarette testing equipment

2010s

Major focus on reduced-risk products

Scientists examining lab sample

2011

BAT and Reynolds R&Ds begin to collaborate

BAT logo on blue background

2017

BAT acquires Reynolds in 2017

BAT Omni logo

2024

BAT launches Omni™

Southampton 70 years of science logo

2026

70 years of Science in Southampton

Today’s multi-disciplinary R&D builds on the strong legacy of those origins, conducting research using multiple core scientific disciplines, aligned to our scientific assessment framework (Figure 1).

This approach to our transformation has married recruiting new talent from other industries, with specific new skillsets, with a focused technical capability development programme for our longer-tenure scientists.

“From pioneering analytical science to advancing modern clinical research, our innovation journey demonstrates how scientific quality, supported by strong capabilities and operational excellence, can turn insight into meaningful change.”


Clio Boura
Head of Science Operations

Figure 1. Our Science Capabilities and our 9-Step Risk Assessment Framework

Diagram showing the nine steps risk assessment framework and the capabilities that support them over time

Footnotes

* Based on the weight of evidence and assuming a complete switch from cigarette smoking. These products are not risk free and are addictive.

Products sold in the U.S., including Vuse, Velo, Grizzly, Kodiak, and Camel Snus, are subject to FDA regulation and no reduced-risk claims will be made as to these products without agency clearance.

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